Fort Myers to Louisville (RSW–SDF) — Airlines, Schedules & Connections

RSW Airport Page →
837 mi airlines 5/wk
On-time Some delays Frequent delays
Flight Schedule 3 flights Verified 29m ago
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  Flight Airline AC Dep Arr Dur OTP Sched  
✈ Nonstop
MX752
MX Mexicana
223
6:19 PM
EDT
8:48 PM
EDT
2h 29m
M T W T F S S
Prices
WN2584
WN Southwest
6:55 PM
EDT
9:03 PM
EDT
2h 8m
M T W T F S S
Prices
MX753
MX Mexicana
223
9:28 PM
EDT
11:53 PM
EDT
2h 25m
M T W T F S S
Prices

No flights match your filters.

No nonstop flights on this route. connecting options below.

1-STOP More options, longer trips
2-STOP Loading... Reach the hardest destinations
Fort Myers to Louisville
2 carriers, 5 flights/week nonstop.
2 Airlines 5 Flights/wk 837 mi 2h 8m nonstop 93 1-stop hubs

RSW–SDF is served by 2 airlines with nonstop service. Mexicana and Southwest Airlines lead the route. The flight covers 837 miles in approximately 2h 8m. Beyond nonstop, 93 hubs offer 1-stop connections.

Airline Landscape

All carriers operating nonstop RSW–SDF service, compared side by side.
Airline Freq/wk Aircraft Duration Dep OTP Alliance Codeshares
MX Mexicana 4 223 2h29 100%
WN Southwest Airlines 1 2h08 100%
Aircraft on this route
223 Airbus A220-300 – MX
Alliance coverage
Unaffiliated: MX + WN (5 flights/wk, 100%)
OTP based on airport-level delay snapshots. Duration ranges reflect seasonal/directional variation.

Weekly Schedule Pattern

Nonstop flight frequency by day of week, RSW to SDF direction.
Mon
1
flight
Tue
0
flights
Wed
0
flights
Thu
1
flight
Fri
1
flight
Sat
0
flights
Sun
2
flights
Departure time distribution
12 AM6 AM12 PM6 PM12 AM
Morning departures
Afternoon/evening departures
2
Nonstop flights
5
Outbound / wk
4
Return / wk

Connection Landscape

Beyond nonstop. 1-stop and 2-stop options for RSW to SDF.
1-STOP
One-Stop Connections
93
Hubs
~3h
Fastest
~29h
Longest
Verified with published schedule alignment and minimum connection time.
2-STOP
Two-Stop Connections
1,722
Candidates
Two-stop connections loaded in the connections tab above.
Connections computed from published schedules with minimum connection time verification. Use the interactive explorer above the fold to filter by airline, tier, and layover time.

Other ways to reach Louisville from Fort Myers

Nearby airports with service to Louisville Muhammad Ali International Airport.
Metric RSW→SDF PGD→SDF SRQ→SDF
Distance from RSW 30 mi 77 mi
Nonstop airlines 2 1 2
Weekly flights 5 5 5
Flight time 2h 8m 2h 18m 1h 54m
Departure OTP 100%
Airports within 200 miles of RSW with service to Louisville Muhammad Ali International Airport.

Travel Essentials

Practical planning for this route.
Time Difference
0h
Louisville is 0 hours the same as Fort Myers.
RSW: EDT · SDF: EDT

When it's 6:00 PM in Fort Myers, it's 6:00 PM in Louisville.
Distance & Flight Time
837 mi / 1,346 km
Nonstop flight time is approximately 2h 8m to 2h 29m.

RSW–SDF Quick Facts

Key statistics for the Fort Myers to Louisville route.
Route details
Distance837 mi / 1,346 km
Flight time2h 8m to 2h 29m
Time difference0 hours
Airlines (nonstop)2
Weekly flights5 out / 4 return
1-stop connections93 hubs
Origin: RSW
IATA / ICAORSW / KRSW
TimezoneAmerica/New_York
Passengers/yr10.9M
Elevation30 ft / 9 m
Destination: SDF
IATA / ICAOSDF / KSDF
TimezoneAmerica/New_York
Passengers/yr4.7M
Elevation501 ft / 153 m

Frequently Asked Questions

Common questions about RSW to SDF flights.
Nonstop flights from Southwest Florida International Airport to Louisville Muhammad Ali International Airport take approximately 2h 8m to 2h 29m. The route covers 837 miles.
2 airlines operate nonstop service: Mexicana and Southwest Airlines.
There are approximately 5 nonstop flights per week from RSW to SDF. The return direction has about 4 weekly flights.
Yes, 1-stop connections are available through TYS, CAE, PDK, BHM, ORL, HHH, OCF, SAV, AGS, SUA, PGD, SRQ, PBI, PIE, GSP, TPA, DNV, CHS, EYW, MEM, BCT, OPF, CVG, CMH, GPT, SUS, PTK, MDT, STL, BKL, IND, PWK, MSY, RIC, YIP, CLE, YHM, TTN, LAN, MKE, YYZ, MMU, TEB, OMA, LSE, ABE, SYR, HOU, ROC, HPN, MCI, MSN, ATW, DAL, BED, RDU, ALB, AUS, MHT, JFK, PSM, SCF, AXA, VNY, PHX, SNA, SJC, IAD, BFI, LAX, SFO, CLT, ATL, IAH, DTW, MCO, ORD, BWI, DEN, BNA, EWR, MDW, DCA, PIT, DFW, PHL, MSP, LGA, FLL, BOS, MIA, LAS and SLC. These options provide additional schedule flexibility.
Yes, return flights from SDF to RSW are available. Use the direction toggle at the top to view the return schedule.
Nearby alternatives include PGD, SRQ and OPF. See the Alternatives section for a full comparison.
Click the 'Search Flights' button to check availability and prices on Google Flights. You can also compare airlines and schedules on this page to find the best option.
See the On-Time Performance section for the latest delay data at both airports. This shows departure and arrival reliability to help you plan.
Route data is updated regularly from official airline schedules. On-time performance data comes from recent airport delay snapshots.

Flights from RSW to SDF

Southwest Florida International Airport (RSW) and Louisville Muhammad Ali International Airport (SDF) are connected by nonstop service from Mexicana and Southwest Airlines. With 5 weekly departures, this is a regularly served route.

RSW to SDF Flight Duration and Schedule

Nonstop flight time from RSW to SDF ranges from 2 hours 8 minutes to 2 hours 29 minutes. The route covers a distance of 837 miles (1,346 km). There are approximately 5 weekly flights outbound and 4 return, totaling 9 flights per week in both directions.

Connecting Options and Alternatives

93 one-stop connections are available, with the fastest taking approximately 3 hours via TYS. Two-stop connections are also available via intermediate hubs. Nearby alternative airports include Punta Gorda (PGD), Sarasota/Bradenton (SRQ) and Miami (OPF).