Harrisburg to Knoxville/Maryville (MDT–TYS) — Airlines, Schedules & Connections

MDT Airport Page →
496 mi airlines charter/private
On-time Some delays Frequent delays
Connecting Flight Schedule 16 1-stop flights Verified 1mo ago
Nonstop Charter / private 1-Stop 2-Stop Hide separate tickets Hide overnight Hide codeshares
  Flight Airline AC Dep Arr Dur OTP Sched  
✈ Nonstop

No flights match your filters.

No scheduled airline flights on this route — it's flown by charter / private operators (). No nonstop flights on this route. connecting options below.

Last scheduled nonstop: Jun 2026.

✦ 1-Stop connections via 10 hubs
IAD Dulles 3h 38m AVCMUA → AVCMET Dulles (IAD) to Knoxville/Maryville flights
ATL Atlanta 3h 46m AFAMDL → AFAMDL Atlanta (ATL) to Knoxville/Maryville flights
CLT Charlotte 3h 51m AA → AAEJA Charlotte (CLT) to Knoxville/Maryville flights
DTW Detroit 4h AFAMDL → AFDLKL Detroit (DTW) to Knoxville/Maryville flights
PHL Philadelphia 4h 10m AAQR → AAASBA Philadelphia (PHL) to Knoxville/Maryville flights
JAX Jacksonville 4h 23m G4 → G4 Jacksonville (JAX) to Knoxville/Maryville flights
ORD Chicago 4h 53m AAASJL → AAASAV Chicago (ORD) to Knoxville/Maryville flights
BNA Nashville 5h 16m G4 → WN Nashville (BNA) to Knoxville/Maryville flights
BOS Boston 5h 20m AA → G4 Boston (BOS) to Knoxville/Maryville flights
PIE Pinellas Park 5h 24m G4 → G4 Pinellas Park (PIE) to Knoxville/Maryville flights
✦ 1-STOP More options, longer trips
✧ 2-STOP Loading... Reach the hardest destinations
Harrisburg to Knoxville/Maryville
Connecting service available through multiple hubs.
1 Airlines 496 mi 2h 11m nonstop

MDT–TYS had nonstop service from Delta Air Lines, last on the schedule in June 2026. There's no nonstop on it right now, so today you'd fly it with one stop. The connecting options below are sorted by layover. Nonstop, it's about 496 miles in 2h 11m.

Also explore MDT Routes TYS Routes MDT Live Flights TYS Live Flights MDT Delays TYS Delays
All flights from Knoxville/Maryville (TYS) Knoxville/Maryville to Harrisburg flights
Carriers on this route

Airline Landscape

Carriers that operated nonstop MDT–TYS service, compared side by side.
Airline Freq/wk Aircraft Duration Dep OTP Alliance Codeshares
DL Delta Air Lines 0 – – 100% SkyTeam –
Alliance coverage
SkyTeam: DL (0 flights/wk, 0%)
OTP based on airport-level delay snapshots. Duration ranges reflect seasonal/directional variation.
Connections

Connection Landscape

1-stop and 2-stop options for MDT to TYS.
1-STOP
One-Stop Connections
16
Hubs
~3h
Fastest
~26h
Longest
IAD ~3h 38m ATL ~3h 46m CLT ~3h 51m DTW ~4h 0m PHL ~4h 10m
Verified with published schedule alignment and minimum connection time.
2-STOP
Two-Stop Connections
334
Candidates
Two-stop connections loaded in the connections tab above.
Connections computed from published schedules with minimum connection time verification. Use the interactive explorer above the fold to filter by airline, tier, and layover time.
Reliability

On-Time Performance

What to expect at each end of your journey.
Outbound
MDT → TYS
100%
Generally reliable. Most flights run on time.
Departing
100%
Arriving
67%
Return
TYS → MDT
100%
Generally reliable. Most flights run on time.
Departing
100%
Arriving
67%
OTP = percentage of flights arriving within 15 min of schedule. Based on airport-level delay snapshots. MDT delays → TYS delays →
Alternatives

Other ways to reach Knoxville/Maryville from Harrisburg

Nearby airports with service to McGhee Tyson Airport.
Metric MDT→TYS HGR→TYS BWI→TYS
Distance from MDT – 61 mi 70 mi
Nonstop airlines – 1 4
Weekly flights – – 12
Flight time 2h 11m 2h 26m 1h 40m
Departure OTP 100% – –
Hagerstown (HGR) to Knoxville/Maryville flights · Baltimore (BWI) to Knoxville/Maryville flights · Wilmington (ILG) to Knoxville/Maryville flights
Airports within 200 miles of MDT with service to McGhee Tyson Airport.
Know before you go

Travel Essentials

Practical planning for this route.
Time Difference
0h
Knoxville/Maryville is 0 hours the same as Harrisburg.
MDT: EDT · TYS: EDT

When it's 6:00 PM in Harrisburg, it's 6:00 PM in Knoxville/Maryville.
Distance & Flight Time
496 mi / 799 km
Nonstop flight time is approximately 2h 11m gate to gate.
Facts

MDT–TYS Quick Facts

Key statistics for the Harrisburg to Knoxville/Maryville route.
Route details
Distance496 mi / 799 km
Flight time2h 11m
Time difference0 hours
Airlines (nonstop)1
1-stop connectionsAvailable
Origin: MDT
Full nameHarrisburg International Airport
IATA / ICAOMDT / KMDT
TimezoneAmerica/New_York
Passengers/yr1.5M
Elevation310 ft / 94 m
Destination: TYS
Full nameMcGhee Tyson Airport
IATA / ICAOTYS / KTYS
TimezoneAmerica/New_York
Passengers/yr3.3M
Elevation981 ft / 299 m
FAQ

Frequently Asked Questions

Common questions about MDT to TYS flights.
Nonstop flights from Harrisburg International Airport to McGhee Tyson Airport take about 2h 11m gate to gate. The route covers 496 miles.
1 airline operated the nonstop from MDT to TYS: Delta Air Lines. The last scheduled nonstop was in June 2026. There's no nonstop right now, so today you'd fly it with one stop. See the connection options above, ranked by layover.
Not right now. The last scheduled nonstop was in June 2026. You can still fly it with one stop, and the connecting options above are sorted by layover. Nonstop, the hop took about 2h 11m.
Yes, 1-stop connections are available, ranked by layover time. Common connecting points include Washington Dulles, Hartsfield Jackson Atlanta and Charlotte Douglas.
Yes, return flights from TYS to MDT are available. Use the direction toggle at the top to view the return schedule.
Nearby alternatives include HGR, BWI and ILG. See the Alternatives section for a full comparison.
Click the 'Search Flights' button to check availability and prices on Google Flights. You can also compare airlines and schedules on this page to find the best option.
See the On-Time Performance section for the latest delay data at both airports. This shows departure and arrival reliability to help you plan.
Route data is updated regularly from official airline schedules. On-time performance data comes from recent airport delay snapshots.

Flights from MDT to TYS

Harrisburg International Airport (MDT) and McGhee Tyson Airport (TYS) had nonstop service from Delta Air Lines, last on the schedule in June 2026. The nonstop is dormant right now, so the way to fly it today is one connection, and the options above are sorted by layover.

MDT to TYS Flight Duration and Schedule

Nonstop flight time from MDT to TYS is about 2 hours 11 minutes gate to gate. The route covers a distance of 496 miles (799 km).

Connecting Options and Alternatives

1-stop connecting options are also available, commonly via Washington Dulles, Hartsfield Jackson Atlanta and Charlotte Douglas. Two-stop connections are also available via intermediate hubs. Nearby alternative airports include Hagerstown (HGR), Baltimore (BWI) and Wilmington (ILG).