Des Moines to St Louis (DSM–STL) — Airlines, Schedules & Connections
No flights match your filters.
No scheduled airline flights on this route — it's flown by charter / private operators (). No nonstop flights on this route. connecting options below.
Most recently operated nonstop flights — the month shown is when each was last scheduled. Most destinations remain reachable with a connection.
No discontinued nonstop flights on record for this route.
DSM–STL had nonstop service from Southwest Airlines, last on the schedule in July 2026. There's no nonstop on it right now, so today you'd fly it with one stop. The connecting options below are sorted by layover. Nonstop, it's about 259 miles in 0h 44m.
Airline Landscape
| Airline | Freq/wk | Aircraft | Duration | Dep OTP | Alliance | Codeshares |
|---|---|---|---|---|---|---|
| WN Southwest Airlines | 0 | – | – | – | – |
Connection Landscape
On-Time Performance
Other ways to reach St Louis from Des Moines
| Metric | DSM→STL | CID→STL | OMA→STL |
|---|---|---|---|
| Distance from DSM | – | 103 mi | 117 mi |
| Nonstop airlines | – | 1 | 3 |
| Weekly flights | – | – | 27 |
| Flight time | 0h 44m | 1h 15m | 1h 11m |
| Departure OTP | 68% | – | – |
Travel Essentials
DSM: CDT · STL: CDT
When it's 6:00 PM in Des Moines, it's 6:00 PM in St Louis.
DSM–STL Quick Facts
Frequently Asked Questions
Flights from DSM to STL
Des Moines International Airport (DSM) and St. Louis Lambert International Airport (STL) had nonstop service from Southwest Airlines, last on the schedule in July 2026. The nonstop is dormant right now, so the way to fly it today is one connection, and the options above are sorted by layover.
DSM to STL Flight Duration and Schedule
Nonstop flight time from DSM to STL is about 0 hours 44 minutes gate to gate. The route covers a distance of 259 miles (417 km).
Connecting Options and Alternatives
1-stop connecting options are also available, commonly via Chicago Midway, Chicago O'Hare and Minneapolis–Saint Paul. Two-stop connections are also available via intermediate hubs. Nearby alternative airports include Cedar Rapids (CID), Omaha (OMA) and Moline (MLI).